Explore single-cell transcriptomics and tissue imaging data from Sid Sijbrandij's osteosarcoma tumor samples — openly shared to advance cancer research.

Interactive visualization of treatment history, MRD measurements, procedures, and imaging from November 2022 to present.

Interactive explorer for bulk RNA-seq gene expression across multiple assays (BostonGene, Tempus, Personalis) with GTEx and PCAWG comparisons, copy number context, and single-cell overlays.

Single-cell RNA-seq from:

GSEA of the single-cell RNA-seq data from tumor. Limma and DESeq2 results from two levels of cell clusters from tumor single-cell RNA-seq from T1, T2, and T3.


UpSet plot of neoantigen mutations across five personalized cancer vaccines (mRNA, JLF V1–V3, CeGaT) with variant allele frequency trends and ELISPOT results.

Interactive genome browser showing ASCAT copy number analysis from whole genome sequencing at two timepoints (T1: June 2024, T2: January 2025).

Interactive IGV genome browser for viewing aligned sequencing data (BAM/BigWig) across WGS, long-read, single-cell, and RNA-seq experiments.
Information about osteosarcoma cell lines including HOS, U-2 OS, and CAL-72 with genomic profiles and curated citations.
25TB of data: bulk WGS, WES, RNA-seq, scRNA-seq, long-read sequencing (ONT), spatial transcriptomics, imaging (H&E, IHC), and HLA typing.
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